Journal article
Uncovering cryptic genetic variation
Abstract
Key PointsCryptic genetic variation (CGV) is genetic variation that is not normally expressed, but that is available to modify abnormal phenotypes produced by environmental or genetic perturbation.CGV is relevant to understanding the expressivity of disease phenotypes, mechanisms of animal and plant breeding, and the relationship between macro- and micro-evolution.CGV is thought to arise as a result of unusually large genotype-by-environment …
Authors
Gibson G; Dworkin I
Journal
Nature Reviews Genetics, Vol. 5, No. 9, pp. 681–690
Publisher
Springer Nature
Publication Date
September 2004
DOI
10.1038/nrg1426
ISSN
1471-0056