Journal article
Endothelial Cell Guidance in 3D Patterned Scaffolds
Abstract
Primary endothelial cells are guided in an agarose hydrogel scaffold that is chemically patterned with an immobilized concentration gradient of VEGF165 using multiphoton laser patterning. It is particularly compelling that, in this 3D patterned hydrogel, endothelial cells differentiate to tip and stalk cells, having the morphology that is observed in vivo.
Authors
Aizawa Y; Wylie R; Shoichet M
Journal
Advanced Materials, Vol. 22, No. 43, pp. 4831–4835
Publisher
Wiley
Publication Date
November 16, 2010
DOI
10.1002/adma.201001855
ISSN
0935-9648