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Antithrombotic drug removal from whole blood using...
Journal article

Antithrombotic drug removal from whole blood using Haemoadsorption with a porous polymer bead sorbent

Abstract

AIM: To evaluate the ability of the DrugSorb™-AntiThrombotic Removal (ATR) haemoadsorption device utilizing porous polymer bead sorbent technology to remove three commonly used antithrombotic drugs from whole blood. METHODS AND RESULTS: We evaluated the removal of apixaban, rivaroxaban, and ticagrelor by the DrugSorb-ATR haemoadsorption device in a benchtop clinical scale model using bovine whole blood. Blood spiked at clinically relevant …

Authors

Tripathi R; Morales J; Lee V; Gibson CM; Mack MJ; Schneider DJ; Douketis J; Sellke FW; Ohman ME; Thourani VH

Journal

European Heart Journal - Cardiovascular Pharmacotherapy, Vol. 8, No. 8, pp. 847–856

Publisher

Oxford University Press (OUP)

Publication Date

December 2, 2022

DOI

10.1093/ehjcvp/pvac036

ISSN

2055-6837