Solid‐Phase Synthesis of Transition Metal Linked, Branched Oligonucleotides

The branched DNA structure 1, in which a transition metal center resides at the branch point and joins two parallel DNA strands, was synthesized by a convergent solid‐phase approach. Complex 1 efficiently hybridizes with complementary DNA to generate transition metal linked DNA duplexes. This opens the door to using the geometries of transition metal complexes to direct the association of DNA into novel motifs.