Journal article
Fluorous ligand capture (FLC): a chemoselective solution-phase strategy for isolating 99m Tc-labelled compounds in high effective specific activity
Abstract
A new approach for preparing (99m)Tc-labelled compounds in high effective specific activity was developed by utilizing a novel fluorous ligand capture (FLC) agent and a chemoselective filtration strategy. This paradigm eliminates the need to use HPLC to obtain technetium(I) based molecular imaging probes free from residual precursor.
Authors
Hicks JW; Harrington LE; Valliant JF
Journal
Chemical Communications, Vol. 47, No. 26, pp. 7518–7520
Publisher
Royal Society of Chemistry (RSC)
Publication Date
2011
DOI
10.1039/c1cc11079a
ISSN
1359-7345