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Journal article

Technetium(I) Complexes of Bathophenanthrolinedisulfonic Acid

Abstract

Bathophenanthrolinedisulfonate (BPS) complexes of technetium(I) of the type [Tc(CO)3(BPS)(L)]n (L = imidazole derivatives) were synthesized and evaluated both in vitro and in vivo. [99mTc(CO)3(BPS)(MeIm)]- (MeIm = 1-methyl-1H-imidazole) was prepared in near-quantitative yield using a convenient two-step, one-pot labeling procedure. A targeted analogue capable of binding regions of calcium turnover associated with bone metabolism was also …

Authors

Yazdani A; Janzen N; Czorny S; Valliant JF

Journal

Inorganic Chemistry, Vol. 56, No. 5, pp. 2958–2965

Publisher

American Chemical Society (ACS)

Publication Date

March 6, 2017

DOI

10.1021/acs.inorgchem.6b03058

ISSN

0020-1669

Labels

McMaster Research Centers and Institutes (RCI)