Journal article
MODL-05. DISCOVERY OF DYNAMIC MINIMAL RESIDUAL DISEASE STATES IN ADULT GLIOBLASTOMA USING SINGLE CELL TECHNOLOGY
Abstract
Abstract
Persister states are proposed oncogenic substrates of disease recurrence in cancer. Recent concepts suggest persisters may occur in dynamic states of the cell cycle (such as cycling and non-cycling states). We therefore investigated biological programs at the post-treatment minimal residual disease (MRD) state following standard chemoradiotherapy in patient-derived xenograft models of GBM. Our analysis of single cell …
Authors
Zador Z; Mikolajewicz N; Han H; Voisin M; Venugopal C; Chokshi C; Maich W; Jason M; Zadeh G; Singh S
Journal
Neuro-Oncology, Vol. 24, No. Supplement_7, pp. vii291–vii292
Publisher
Oxford University Press (OUP)
Publication Date
November 14, 2022
DOI
10.1093/neuonc/noac209.1133
ISSN
1522-8517