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Cancer risk with topical calcineurin inhibitors,...
Journal article

Cancer risk with topical calcineurin inhibitors, pimecrolimus and tacrolimus, for atopic dermatitis: a systematic review and meta-analysis

Abstract

BACKGROUND: Atopic dermatitis is a prevalent condition in children and can be effectively managed with medications such as topical calcineurin inhibitors (pimecrolimus or tacrolimus). A key unresolved safety concern is whether use of topical calcineurin inhibitors is associated with cancer. We systematically reviewed the risk of cancer in patients with atopic dermatitis exposed to topical calcineurin inhibitors. METHODS: As part of the 2022 …

Authors

Devasenapathy N; Chu A; Wong M; Srivastava A; Ceccacci R; Lin C; MacDonald M; Wen A; Steen J; Levine M

Journal

The Lancet Child & Adolescent Health, Vol. 7, No. 1, pp. 13–25

Publisher

Elsevier

Publication Date

January 2023

DOI

10.1016/s2352-4642(22)00283-8

ISSN

2352-4642