Journal article
Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti
Abstract
The genome of about 10% of bacterial species is divided among two or more large chromosome-sized replicons. The contribution of each replicon to the microbial life cycle (for example, environmental adaptations and/or niche switching) remains unclear. Here we report a genome-scale metabolic model of the legume symbiont Sinorhizobium meliloti that is integrated with carbon utilization data for 1,500 genes with 192 carbon substrates. Growth of S. …
Authors
diCenzo GC; Checcucci A; Bazzicalupo M; Mengoni A; Viti C; Dziewit L; Finan TM; Galardini M; Fondi M
Journal
Nature Communications, Vol. 7, No. 1,
Publisher
Springer Nature
DOI
10.1038/ncomms12219
ISSN
2041-1723