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Intraoperative Inspiratory Oxygen Fraction and...
Journal article

Intraoperative Inspiratory Oxygen Fraction and Myocardial Injury After Noncardiac Surgery: Results From an International Observational Study in Relation to Recent Controlled Trials

Abstract

BACKGROUND: Two trials reported that a high inspiratory oxygen fraction (F io2 ) does not promote myocardial infarction or death. Observational studies can provide larger statistical strength, but associations can be due to unobserved confounding. Therefore, we evaluated the association between intraoperative F io2 and cardiovascular complications in a large international cohort study to see if spurious associations were observed. METHODS: We …

Authors

Pedersen SS; Holse C; Mathar CE; Chan MTV; Sessler DI; Liu Y; Zhang L; Kurz A; Jacka M; Torborg A

Journal

Anesthesia & Analgesia, Vol. 135, No. 5, pp. 1021–1030

Publisher

Wolters Kluwer

Publication Date

November 2022

DOI

10.1213/ane.0000000000006042

ISSN

0003-2999