Journal article
Sex-Specific Functional Specialization and the Evolutionary Rates of Essential Fertility Genes
Abstract
Genes related to sex and reproduction are known to evolve rapidly, however, the mechanism for rapid evolutionary change is proving to be more complex than a simple relaxation of selective constraint. We compared the divergence between orthologous human and mouse fertility genes according to their degree of dispensability as suggested by mouse knockout mutation phenotypes. The dataset consisted of 161 orthologous genes affecting fertility and …
Authors
Torgerson DG; Whitty BR; Singh RS
Journal
Journal of Molecular Evolution, Vol. 61, No. 5, pp. 650–658
Publisher
Springer Nature
Publication Date
November 2005
DOI
10.1007/s00239-005-0007-5
ISSN
0022-2844