Human Adenovirus Vectors for Gene Transfer into Mammalian Cells

Publisher The high efficiency of gene transfer mediated by recombinant Adenovirus (Ad) has prompted the construction of dozens of first-generation Ad vectors for high level transgene expression in mammalian cells. These vectors have been designed and employed for uses as diverse as recombinant protein production and characterization, transcriptional analysis, establishment of stably transformed cell lines, and gene therapy. As the Ad vector …