Obstructive and Sclerotic Disorders affecting Carotid Blood Flow to the Brain

The carotid artery is one of the major supply routes of blood to the brain. Currently, it is unknown what impact local changes within the carotid artery have on global circulation and specifically on the pressure and flow relationship in the common carotid artery (CCA) to the internal carotid artery (ICA) and eventually into the cerebral circulation. We used a lumped parameter model matched to an in vitro flow loop to study the effects of local …