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Research interrupted: applying the CONSERVE 2021...
Journal article

Research interrupted: applying the CONSERVE 2021 Statement to a randomized trial of rehabilitation during critical illness affected by the COVID-19 pandemic

Abstract

RationaleThe COVID-19 pandemic disrupted non-COVID critical care trials globally as intensive care units (ICUs) prioritized patient care and COVID-specific research. The international randomized controlled trial CYCLE (Critical Care Cycling to Improve Lower Extremity Strength) was forced to halt recruitment at all sites in March 2020, creating immediate challenges. We applied the CONSERVE (CONSORT and SPIRIT Extension for RCTs Revised in …

Authors

Reid JC; Molloy A; Strong G; Kelly L; O’Grady H; Cook D; Archambault PM; Ball I; Berney S; Burns KEA

Journal

Trials, Vol. 23, No. 1,

Publisher

Springer Nature

DOI

10.1186/s13063-022-06640-y

ISSN

1468-6708