Journal article
The effects of low-level lead exposure in developing rats: changes in circadian locomotor activity and hippocampal noradrenaline turnover
Abstract
The circadian spontaneous locomotor activity of rats exposed to 0.1 mg lead/kg, po from 3 days until 4 and 6 weeks of age was similar to that of controls. However, hyperactivity during initial hours of recording was observed in rats that were treated with lead (Pb) until 8 weeks of age. When treatment was discontinued for 2 weeks, previously Pb-exposed rats had a tendency to be hypoactive. The elevated locomotor activity in 8-week-old …
Authors
Collins MF; Hrdina PD; Whittle E; Singhal RL
Journal
Canadian Journal of Physiology and Pharmacology, Vol. 62, No. 4, pp. 430–435
Publisher
Canadian Science Publishing
Publication Date
April 1, 1984
DOI
10.1139/y84-068
ISSN
0008-4212