Journal article
eQTL Set-Based Association Analysis Identifies Novel Susceptibility Loci for Barrett Esophagus and Esophageal Adenocarcinoma.
Abstract
BACKGROUND: Over 20 susceptibility single-nucleotide polymorphisms (SNP) have been identified for esophageal adenocarcinoma (EAC) and its precursor, Barrett esophagus (BE), explaining a small portion of heritability.
METHODS: Using genetic data from 4,323 BE and 4,116 EAC patients aggregated by international consortia including the Barrett's and Esophageal Adenocarcinoma Consortium (BEACON), we conducted a comprehensive transcriptome-wide …
Authors
Wang X; Gharahkhani P; Levine DM; Fitzgerald RC; Gockel I; Corley DA; Risch HA; Bernstein L; Chow W-H; Onstad L
Journal
Cancer Epidemiology Biomarkers & Prevention, Vol. 31, No. 9, pp. 1735–1745
Publisher
American Association for Cancer Research (AACR)
Publication Date
September 2, 2022
DOI
10.1158/1055-9965.epi-22-0096
ISSN
1055-9965