Journal article
Abstract LB-147: Characterization of a Kaiso overexpressing transgenic mouse model
Abstract
Abstract
Introduction: The WNT signaling pathway plays critical roles during embryogenesis and maintaining homeostasis of adult tissues. However constitutive WNT signaling leads to tumorigenesis. Upon activation of the WNT pathway, the main downstream effector of the WNT pathway, ß-catenin, stabilizes and translocates to the nucleus where it activates transcription of WNT target genes. Recently, our lab along with others …
Authors
Chaudhary R; Nanan KK; Daniel JM
Journal
Cancer Research, Vol. 70, No. 8_Supplement,
Publisher
American Association for Cancer Research (AACR)
Publication Date
April 15, 2010
DOI
10.1158/1538-7445.am10-lb-147
ISSN
0008-5472