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Abstract LB-271: The biological role of the...
Journal article

Abstract LB-271: The biological role of the transcription factor Kaiso in breast tumorigenesis

Abstract

Abstract Introduction: The canonical Wnt signalling pathway regulates various cellular processes (e.g. proliferation, differentiation, apoptosis) and leads to tumorigenesis when aberrantly activated. -catenin, the key downstream effector in Wnt signalling, translocates to the nucleus upon Wnt pathway activation, and activates target genes involved in tumorigenesis. The transcription factor Kaiso is a novel BTB/POZ (Broad …

Authors

Weerawardane S; Daniel JM

Journal

Cancer Research, Vol. 70, No. 8_Supplement,

Publisher

American Association for Cancer Research (AACR)

Publication Date

April 15, 2010

DOI

10.1158/1538-7445.am10-lb-271

ISSN

0008-5472