Journal article
Topical therapy with negative allosteric modulators of the calcium-sensing receptor (calcilytics) for the management of asthma: the beginning of a new era?
Abstract
In this review article we present the evidence to date supporting the role of the calcium-sensing receptor (CaSR) as a key, pluripotential molecular trigger for asthma and speculate on the likely benefits of topical therapy of asthma with negative allosteric modulators of the CaSR: calcilytics.
Authors
Riccardi D; Ward JPT; Yarova PL; Janssen LJ; Lee TH; Ying S; Corrigan CJ
Journal
European Respiratory Journal, Vol. 60, No. 2,
Publisher
European Respiratory Society (ERS)
Publication Date
August 2022
DOI
10.1183/13993003.02103-2021
ISSN
0903-1936