Management of immune‐mediated thrombocytopenia

Low circulating platelet numbers can be caused by platelet underproduction, sequestration, hemodilution, consumption, or destruction. This chapter explores the problem of immune‐mediated thrombocytopenia, including autoimmune conditions, secondary immune conditions, and alloimmune conditions. Platelets are usually quantitated during a complete blood cell count with a particle counter. Various monoclonal antibody‐based assays can be used to …