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The influence of track structure on the...
Journal article

The influence of track structure on the understanding of relative biological effectiveness for induction of chromosomal exchanges in human lymphocytes.

Abstract

A biophysical model has been applied to describe the production of exchange chromosomal aberrations (dicentrics) in human lymphocytes by radiations of different qualities. The model includes a detailed description of the energy deposition pattern in the form of computer-generated tracks. Energy deposition events are further converted to DNA double-strand breaks (DSBs). Formation of chromosomal exchanges is modeled in competition with repair in …

Authors

Moiseenko VV; Edwards AA; Nikjoo H; Prestwich WV

Journal

Radiation Research, Vol. 147, No. 2, pp. 208–214

Publisher

JSTOR

Publication Date

February 1997

DOI

10.2307/3579422

ISSN

0033-7587