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Autoantibodies to Thrombopoietin and the...

Journal article

Autoantibodies to Thrombopoietin and the Thrombopoietin Receptor in Patients with Immune Thrombocytopenia

Abstract

Abstract Background: Primary immune thrombocytopenia (ITP) is an autoimmune bleeding disorder caused by autoantibodies against platelet glycoproteins (GP). These autoantibodies are detected in only 40-60% of ITP patients even when sensitive techniques are used. Our understanding of the mechanisms of ITP is limited by the variability in clinical presentation, varied differences in treatment responses and the lack of reliable …

Authors

Nazy I; Moore JC; Clare R; Smith JW; Ivetic N; D'Souza V; Kelton JG; Arnold DM

Journal

Blood, Vol. 128, No. 22, pp. 2548–2548

Publisher

American Society of Hematology

Publication Date

December 2, 2016

DOI

10.1182/blood.v128.22.2548.2548

ISSN

0006-4971

Associated Experts

Donald Arnold

Professor, Faculty of Health Sciences

Labels

Fields of Research (FoR)

3101 Biochemistry and cell biology 3201 Cardiovascular medicine and haematology 3213 Paediatrics

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