A Single Dose of Exercise Initiates Corrective Mitochondrial Plasticity in Myotonic Dystrophy Type 1

Myotonic dystrophy type 1 (DM1) is the most common life‐limiting muscular dystrophy in adults. Abnormal mitochondrial function and dynamics have been observed in DM1 patient derived cells, which likely exacerbates the muscle pathology in DM1. Exercise is safe, low‐cost, and accessible medicine that reaps robust benefits to mitochondrial biology. However, in DM1 muscle, in vivo assessments of mitochondrial dynamics and mitophagy, as well as the …