Journal article
Mouse models of immune dysfunction: their neuroanatomical differences reflect their anxiety-behavioural phenotype
Abstract
Extensive evidence supports the role of the immune system in modulating brain function and behaviour. However, past studies have revealed striking heterogeneity in behavioural phenotypes produced from immune system dysfunction. Using magnetic resonance imaging, we studied the neuroanatomical differences among 11 distinct genetically modified mouse lines (n = 371), each deficient in a different element of the immune system. We found a …
Authors
Fernandes DJ; Spring S; Corre C; Tu A; Qiu LR; Hammill C; Vousden DA; Spencer Noakes TL; Nieman BJ; Bowdish DME
Journal
Molecular Psychiatry, Vol. 27, No. 7, pp. 3047–3055
Publisher
Springer Nature
Publication Date
July 2022
DOI
10.1038/s41380-022-01535-5
ISSN
1359-4184