Journal article
RUNX2 tandem repeats and the evolution of facial length in placental mammals
Abstract
BackgroundWhen simple sequence repeats are integrated into functional genes, they can potentially act as evolutionary ‘tuning knobs’, supplying abundant genetic variation with minimal risk of pleiotropic deleterious effects. The genetic basis of variation in facial shape and length represents a possible example of this phenomenon. Runt-related transcription factor 2 (RUNX2), which is involved in osteoblast differentiation, contains a …
Authors
Pointer MA; Kamilar JM; Warmuth V; Chester SGB; Delsuc F; Mundy NI; Asher RJ; Bradley BJ
Journal
BMC Ecology and Evolution, Vol. 12, No. 1,
Publisher
Springer Nature
Publication Date
12 2012
DOI
10.1186/1471-2148-12-103
ISSN
1472-6785