STAGE as a multicenter, multivendor protocol for imaging Parkinson’s disease: a validation study on healthy controls

PurposeIt is becoming increasingly important to develop imaging biomarkers to study Parkinson’s disease (PD) and movement disorders. A number of key new biomarkers in magnetic resonance imaging (MRI) include measuring proton spin density (PSD), T1, iron content and volumes of the deep gray matter and neuromelanin. A new rapid, multi-contrast, multi-parametric quantitative MRI method referred to as strategically acquired gradient echo (STAGE) …