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TAMI-03. IDENTIFICATION OF NOVEL DRIVERS OF...
Journal article

TAMI-03. IDENTIFICATION OF NOVEL DRIVERS OF LUNG-TO-BRAIN METASTASIS THROUGH IN VIVO FUNCTIONAL GENOMICS

Abstract

Abstract Brain metastasis, the most common tumor of the central nervous system, occurs in 20-36% of primary cancers. In particular, 40% of patients with non-small cell lung cancer (NSCLC) develop brain metastases, with a dismal survival of approximately 4-11 weeks without treatment, and 16 months with treatment. This highlights a large unmet need to develop novel targeted therapies for the treatment of lung-to-brain metastases …

Authors

Aghaei N; Lam F; Venugopal C; Singh S

Journal

Neuro-Oncology, Vol. 22, No. Supplement_2, pp. ii213–ii213

Publisher

Oxford University Press (OUP)

Publication Date

November 9, 2020

DOI

10.1093/neuonc/noaa215.892

ISSN

1522-8517

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