Journal article
A248 THE ROLE OF DIETARY TRYPTOPHAN IN INDOLE AND KYNURENINE PRODUCTION AND IMMUNE MODULATION IN HEALTHY INDIVIDUALS
Abstract
AbstractBackground
Natural supplements are widely consumed by the general public, with little evidence of mechanistic support. Tryptophan has gained central attention, being transformed by host and gut microbial enzymes into multiple bioactive metabolites that regulate immunity and mood. Indoles are activators of the aryl hydrocarbon receptor (AhR), crucial for the maintenance of intestinal homeostasis. Tryptophan has been advocated to prevent …
Authors
Rueda GH; Causada-Calo N; Nardelli A; Pinto-Sanchez MI; Borojevic R; Libertucci J; Loonen L; Wells J; Sokol H; Verdu E
Journal
Journal of the Canadian Association of Gastroenterology, Vol. 5, No. Supplement_1, pp. 141–142
Publisher
Oxford University Press (OUP)
Publication Date
February 21, 2022
DOI
10.1093/jcag/gwab049.247
ISSN
2515-2084