Journal article
Comparison of efficacy of a 7-day versus a 14-day course of intravenous antibiotics in the treatment of uncomplicated neonatal bacterial sepsis: study protocol of a randomized controlled non-inferiority trial
Abstract
BackgroundNeonatal sepsis is a global public health problem. There is no consensus regarding the optimum duration of antibiotics for culture-proven neonatal sepsis. Published randomized controlled trials (RCTs) comparing shorter versus longer courses of antibiotics provide low-quality evidence with serious risk of bias. We hypothesized that among neonates with uncomplicated culture-proven sepsis, antibiotic duration of 7 days is not inferior to …
Authors
Dutta S; Nangia S; Jajoo M; Gathwala G; Nesargi S; Sundaram M; Kumar P; Saili A; Kumar D; Dalal P
Journal
Trials, Vol. 22, No. 1,
Publisher
Springer Nature
Publication Date
12 2021
DOI
10.1186/s13063-021-05785-6
ISSN
1468-6708