Journal article
Pretreatment with a combination of ligustrazine and berberine improves cardiac function in rats with coronary microembolization
Abstract
Aim:We have shown that a combination of ligustrazine and berberine produces more effective inhibition on platelet activation and inflammatory reactions in rat acute myocardial infarction compared with either agent alone. In this study we evaluated the beneficial effects of a combination of ligustrazine and berberine in a rat model of coronary microembolization (CME).Methods:SD rats were treated with ligustrazine, berberine, …
Authors
Zhang Y; Ma X-J; Guo C-Y; Wang M-M; Kou N; Qu H; Mao H-M; Shi D-Z
Journal
Acta Pharmacologica Sinica, Vol. 37, No. 4, pp. 463–472
Publisher
Springer Nature
Publication Date
April 2016
DOI
10.1038/aps.2015.147
ISSN
1671-4083