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A Monte Carlo and physical phantom evaluation of...
Journal article

A Monte Carlo and physical phantom evaluation of quantitative In-111 SPECT

Abstract

Accurate estimation of the 3D in vivo activity distribution is important for dose estimation in targeted radionuclide therapy (TRT). Although SPECT can potentially provide such estimates, SPECT without compensation for image degrading factors is not quantitatively accurate. In this work, we evaluated quantitative SPECT (QSPECT) reconstruction methods that include compensation for various physical effects. Experimental projection data were …

Authors

He B; Du Y; Song X; Segars WP; Frey EC

Journal

Physics in Medicine and Biology, Vol. 50, No. 17, pp. 4169–4185

Publisher

IOP Publishing

Publication Date

September 7, 2005

DOI

10.1088/0031-9155/50/17/018

ISSN

0031-9155