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The Effect of Lactate on the Radiation Response of...
Journal article

The Effect of Lactate on the Radiation Response of CHO-K1 Cells in Culture

Abstract

The radiobiological effect of lactate is described. Prolonged incubation of CHO-K1 cells over a wide range of lactate concentrations sensitized them to subsequent irradiation. Survival curves indicated that the size of the shoulder was reduced. Short treatment times resulted in a radioprotective effect and an increase in the survival curve slope. Lactate levels used were within physiological limits and are therefore discussed in relation to …

Authors

Seymour CB; Mothersill C

Journal

International Journal of Radiation Biology, Vol. 40, No. 3, pp. 283–291

Publisher

Taylor & Francis

Publication Date

1 1981

DOI

10.1080/09553008114551201

ISSN

0955-3002