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Radiosensitization of colon cancer cell lines by...
Journal article

Radiosensitization of colon cancer cell lines by docetaxel: mechanisms of action.

Abstract

The radiation-modifying action of docetaxel in experimental systems is well established. Docetaxel is also an increasingly important drug for the treatment of cancer in concurrent radiotherapy protocols. However, the mechanisms of docetaxel radiosensitization are not fully understood. We have investigated the magnitude and mechanisms of docetaxel radiosensitization in vitro in four human colorectal cancer cell lines (SW480, SW707, SW48, and …

Authors

Dunne AL; Mothersill C; Robson T; Wilson GD; Hirst DG

Journal

Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics, Vol. 14, No. 9, pp. 447–454

Publisher

Tech Science Press

Publication Date

2004

DOI

10.3727/0965040041791455

ISSN

0965-0407