Prevention and Treatment of Thrombotic Antiphospholipid Syndrome

Antiphospholipid syndrome (APS) is a clinical syndrome characterized by macro- and/or microvascular thrombosis and pregnancy morbidity, with laboratory criteria including persistently positive lupus anticoagulant and/or anticardiolipin antibody and/or anti-β2 glycoprotein-1 antibody. Patients with antiphospholipid antibodies (aPL) appear to be at increased risk of thrombosis. Primary prophylaxis with aspirin is probably indicated to reduce the …