A Prospective Cohort Study of the Epidemiology of Symptomatic Venous Thromboembolism (VTE) after Isolated Leg Fractures Distal to the Knee without Thromboprophylaxis.

Abstract The reported incidence of deep vein thrombosis (DVT) using routine venography in patients with isolated leg fractures distal to the knee is as high as 40%. However venography is a very sensitive screening test primarily detecting asymptomatic, distal thrombi whose clinical relevance is uncertain. Therefore venography may not be the best outcome measure to assess the clinical burden of symptomatic VTE, or as an …