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Use of novel antithrombotic agents for COVID‐19:...
Journal article

Use of novel antithrombotic agents for COVID‐19: Systematic summary of ongoing randomized controlled trials

Abstract

BACKGROUND: Coronavirus disease 2019 (COVID-19) is associated with macro- and micro-thromboses, which are triggered by endothelial cell activation, coagulopathy, and uncontrolled inflammatory response. Conventional antithrombotic agents are under assessment in dozens of randomized controlled trials (RCTs) in patients with COVID-19, with preliminary results not demonstrating benefit in several studies. OBJECTIVES: Given the possibility that more …

Authors

Talasaz AH; Sadeghipour P; Aghakouchakzadeh M; Kakavand H; Ariannejad H; Connors JM; Hunt BJ; Berger JS; Van Tassell BW; Middeldorp S

Journal

Journal of Thrombosis and Haemostasis, Vol. 19, No. 12, pp. 3080–3089

Publisher

Elsevier

Publication Date

12 2021

DOI

10.1111/jth.15533

ISSN

1538-7933