Journal article
Use of novel antithrombotic agents for COVID‐19: Systematic summary of ongoing randomized controlled trials
Abstract
BACKGROUND: Coronavirus disease 2019 (COVID-19) is associated with macro- and micro-thromboses, which are triggered by endothelial cell activation, coagulopathy, and uncontrolled inflammatory response. Conventional antithrombotic agents are under assessment in dozens of randomized controlled trials (RCTs) in patients with COVID-19, with preliminary results not demonstrating benefit in several studies.
OBJECTIVES: Given the possibility that more …
Authors
Talasaz AH; Sadeghipour P; Aghakouchakzadeh M; Kakavand H; Ariannejad H; Connors JM; Hunt BJ; Berger JS; Van Tassell BW; Middeldorp S
Journal
Journal of Thrombosis and Haemostasis, Vol. 19, No. 12, pp. 3080–3089
Publisher
Elsevier
Publication Date
December 2021
DOI
10.1111/jth.15533
ISSN
1538-7933