Journal article
Sex Differences and the Role of Sex Hormones in Pulmonary Hypertension
Abstract
Pulmonary arterial hypertension is characterized by progressive pulmonary vascular remodeling and the eventual development of right heart failure. Multiple mechanisms are responsible, including vasoconstriction, metabolic flux, and inflammation. Since the early descriptions of pulmonary hypertension, female sex has been associated with increased prevalence of the disease, with research showing both detrimental and beneficial effects of estrogen …
Authors
Oakland HT; Joseph P
Journal
Clinics in Chest Medicine, Vol. 42, No. 3, pp. 457–465
Publisher
Elsevier
Publication Date
9 2021
DOI
10.1016/j.ccm.2021.04.006
ISSN
0272-5231