Journal article
Multiple Genetic Loci Influence Serum Urate Levels and Their Relationship With Gout and Cardiovascular Disease Risk Factors
Abstract
BACKGROUND: Elevated serum urate levels can lead to gout and are associated with cardiovascular risk factors. We performed a genome-wide association study to search for genetic susceptibility loci for serum urate and gout and investigated the causal nature of the associations of serum urate with gout and selected cardiovascular risk factors and coronary heart disease (CHD).
METHODS AND RESULTS: Meta-analyses of genome-wide association studies …
Authors
Yang Q; Köttgen A; Dehghan A; Smith AV; Glazer NL; Chen M-H; Chasman DI; Aspelund T; Eiriksdottir G; Harris TB
Journal
Circulation Genomic and Precision Medicine, Vol. 3, No. 6, pp. 523–530
Publisher
Wolters Kluwer
Publication Date
12 2010
DOI
10.1161/circgenetics.109.934455
ISSN
1942-325X