Journal article
Promises and challenges of pharmacogenetics: an overview of study design, methodological and statistical issues
Abstract
Pharmacogenetics is the study of inherited variation in drug response. The goal of pharmacogenetics is to develop novel ways of maximizing drug efficacy and minimizing toxicity for individual patients. Personalized medicine has the potential to allow for a patient's genetic information to predict optimal dosage for a drug with a narrow therapeutic index, to select the most appropriate pharmacological agent for a given patient and to develop …
Authors
Ross S; Anand SS; Joseph P; Paré G
Journal
JRSM Cardiovascular Disease, Vol. 1, No. 1, pp. 1–13
Publisher
SAGE Publications
Publication Date
4 2012
DOI
10.1258/cvd.2012.012001
ISSN
2048-0040