The 9p21.3 locus and cardiovascular risk in familial hypercholesterolemia

Abstract

BACKGROUND: Carrying a risk variant in the 9p21.3 locus represents one of the strongest genetic risk factors for atherosclerotic cardiovascular disease (ASCVD) in the general population. However, the effect of these polymorphisms in patients with familial hypercholesterolemia (FH) has never been studied. OBJECTIVE: The objective of this study was to investigate the association between the sentinel 9p21.3 single nucleotide polymorphisms (SNP) …

Authors

Paquette M; Chong M; Saavedra YGL; Paré G; Dufour R; Baass A

Journal

Journal of Clinical Lipidology, Vol. 11, No. 2, pp. 406–412

Publisher

Elsevier

Publication Date

3 2017

DOI

10.1016/j.jacl.2017.01.012

ISSN

1933-2874

Associated Experts

Guillaume Pare

Professor, Faculty of Health Sciences

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