Journal article
Elevated expression of the interleukin 4 receptor in carcinoma: a target for immunotherapy?
Abstract
Studies using monoclonal antibody MR6, which is thought to bind to the interleukin-4 growth factor receptor (IL-4R), indicate that IL-4R molecules are upregulated in tumours of epithelial origin and that radiolabelled MR6 is effective as an in vivo tumour imaging agent. Immunohistochemical analysis of a wide range of solid tumours using monoclonal antibody MR6 has demonstrated elevated expression of the IL-4R on a variety of carcinomas. The …
Authors
Al Jabaari B; Ladyman H; Larché M; Sivolapenko G; Epenetos A; Ritter M
Journal
British Journal of Cancer, Vol. 59, No. 6, pp. 910–914
Publisher
Springer Nature
Publication Date
6 1989
DOI
10.1038/bjc.1989.192
ISSN
0007-0920