Journal article
Modelling the human immune response: can mice be trusted?
Abstract
The mouse is now the animal of choice for laboratory-based medical research. Although its contribution to advancing understanding of our inner workings is indisputable, we should acknowledge that mice and humans are tangibly different. This article highlights, and attempts some rationale for, discrepancies between the two species' immune systems.
Authors
Gordon J; Grafton G; Wood PM; Larché M; Armitage RJ
Journal
Current Opinion in Pharmacology, Vol. 1, No. 4, pp. 431–435
Publisher
Elsevier
Publication Date
August 1, 2001
DOI
10.1016/s1471-4892(01)00074-1
ISSN
1471-4892