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H-Ras gene takes part to the host immune response...
Journal article

H-Ras gene takes part to the host immune response to COVID-19

Abstract

Ras gene family members play a relevant role in cancer, especially when they are mutated. However, they may play additional roles in other conditions beside cancer. We performed gene expression analysis using the NanoString PanCancer IO 360 panel in the peripheral blood mononuclear cell (PBMC) of six COVID-19 patients and we found that H-Ras gene was significantly upregulated, while both K-Ras and N-Ras genes were downregulated. In particular, …

Authors

Sciacchitano S; Sacconi A; De Vitis C; Blandino G; Piaggio G; Salvati V; Napoli C; Marchetti P; Taurelli BS; Coluzzi F

Journal

Cell Death Discovery, Vol. 7, No. 1,

Publisher

Springer Nature

DOI

10.1038/s41420-021-00541-w

ISSN

2058-7716