Journal article
Three week compared to seven week run-in period length and the assessment of pre-randomization adherence: A study within a trial
Abstract
BACKGROUND/AIMS: To examine how measuring adherence at 3 weeks by self-report and pill counts compares to measurements at 7 weeks in a pre-randomization run-in period.
METHODS: Study within a trial of an international parallel group randomized controlled trial (RCT) that compares spironolactone to placebo. Adults receiving dialysis enter an 8-week active run-in period with spironolactone. Adherence was assessed by both self-report and pill …
Authors
Collister D; Mbuagbaw L; Guyatt G; Devereaux PJ; Tennankore KK; Reis G; Sola L; Xavier D; Jha V; Gallagher M
Journal
Contemporary Clinical Trials, Vol. 107, ,
Publisher
Elsevier
Publication Date
8 2021
DOI
10.1016/j.cct.2021.106466
ISSN
1551-7144