Journal article
Deep Brain Stimulation for Treatment-Resistant Depression
Abstract
Treatment-resistant depression is a severely disabling disorder with no proven treatment options once multiple medications, psychotherapy, and electroconvulsive therapy have failed. Based on our preliminary observation that the subgenual cingulate region (Brodmann area 25) is metabolically overactive in treatment-resistant depression, we studied whether the application of chronic deep brain stimulation to modulate BA25 could reduce this …
Authors
Mayberg HS; Lozano AM; Voon V; McNeely HE; Seminowicz D; Hamani C; Schwalb JM; Kennedy SH
Journal
FOCUS The Journal of Lifelong Learning in Psychiatry, Vol. 6, No. 1, pp. 143–154
Publisher
American Psychiatric Association Publishing
Publication Date
January 2008
DOI
10.1176/foc.6.1.foc143
ISSN
1541-4094