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901PD Association of Progression by Prostate...
Journal article

901PD Association of Progression by Prostate Cancer Working Group (PCWG)-2 Criteria and Survival in Metastatic Castration Resistant Prostate Cancer

Abstract

Background Intermediate endpoints to identify active agents for metastatic castration-resistant prostate cancer (mCRPC) are suboptimal. The Prostate Cancer Working Group (PCWG)-2 guidelines recommend time to clinical or radiographic event endpoints, and discouraged use of endpoints using PSA changes. We investigated the association of progression defined by PCWG-2 guidelines and overall survival (OS). Methods Two trials were analyzed: CS-205, a …

Authors

Sonpavde G; Pond GR; Armstrong AJ; Galsky MD; Wood BA; Wang S; Paolini J; Lechuga M; Smith MR; Michaelson MD

Journal

Annals of Oncology, Vol. 23, , pp. ix297–ix298

Publisher

Elsevier

Publication Date

September 2012

DOI

10.1016/s0923-7534(20)33529-8

ISSN

0923-7534