A300 DIET-MICROBIOTA INTERACTIONS UNDERLIE SYMPTOMS IN IBS

The mechanisms underlying IBS are poorly understood but growing evidence suggests that immune activation and the microbiota may be involved. We recently demonstrated that a diet low in fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) improves symptoms in IBS patients and this is correlated with decreased mast cell activation and changes in the microbiota composition. Thus, FODMAPs may be a useful tool to …