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Changes in the Brain‐Derived Neurotrophic Factor...
Journal article

Changes in the Brain‐Derived Neurotrophic Factor Are Associated with Improvements in Diabetes Risk Factors after Exercise Training in Adolescents with Obesity: The HEARTY Randomized Controlled Trial

Abstract

Obesity in youth increases the risk of type 2 diabetes (T2D), and both are risk factors for neurocognitive deficits. Exercise attenuates the risk of obesity and T2D while improving cognitive function. In adults, these benefits are associated with the actions of the brain-derived neurotrophic factor (BDNF), a protein critical in modulating neuroplasticity, glucose regulation, fat oxidation, and appetite regulation in adults. However, little …

Authors

Walsh JJ; D’Angiulli A; Cameron JD; Sigal RJ; Kenny GP; Holcik M; Doucette S; Alberga AS; Prud’homme D; Hadjiyannakis S

Journal

Neural Plasticity, Vol. 2018, No. 1,

Publisher

Hindawi

Publication Date

September 30, 2018

DOI

10.1155/2018/7169583

ISSN

2090-5904