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Role of Intestinal Bacteria in Gliadin-Induced...
Journal article

Role of Intestinal Bacteria in Gliadin-Induced Changes in Intestinal Mucosa: Study in Germ-Free Rats

Abstract

BACKGROUND AND AIMS: Celiac disease (CD) is a chronic inflammatory disorder of the small intestine that is induced by dietary wheat gluten proteins (gliadins) in genetically predisposed individuals. The overgrowth of potentially pathogenic bacteria and infections has been suggested to contribute to CD pathogenesis. We aimed to study the effects of gliadin and various intestinal bacterial strains on mucosal barrier integrity, gliadin …

Authors

Cinova J; De Palma G; Stepankova R; Kofronova O; Kverka M; Sanz Y; Tuckova L

Journal

PLOS ONE, Vol. 6, No. 1,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pone.0016169

ISSN

1932-6203