Journal article
α-Synuclein and neuronal membranes: Conformational flexibilities in health and disease
Abstract
Parkinson's disease (PD) is the second most common neurodegenerative disease. Currently, PD has no treatment. The neuronal protein α-synuclein (αS) plays an important role in PD. However, the molecular mechanisms governing its physiological and pathological roles are not fully understood. It is becoming widely acknowledged that the biological roles of αS involve interactions with biological membranes. In these biological processes there is a …
Authors
Bozelli JC; Kamski-Hennekam E; Melacini G; Epand RM
Journal
Chemistry and Physics of Lipids, Vol. 235, ,
Publisher
Elsevier
Publication Date
March 2021
DOI
10.1016/j.chemphyslip.2020.105034
ISSN
0009-3084